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VEGFA

VEGFA,即血管內(nèi)皮生長(zhǎng)因子A(Vascular Endothelial Growth Factor A),是一種關(guān)鍵的血管生成調(diào)節(jié)因子,由多種細(xì)胞類型分泌,包括內(nèi)皮細(xì)胞、巨噬細(xì)胞和腫瘤細(xì)胞。其作用機(jī)制主要通過與其特異性酪氨酸激酶受體VEGFR1和VEGFR2結(jié)合,特別是VEGFR2,激活下游的信號(hào)傳導(dǎo)途徑,如JAK-STAT、MAPK和PI3K等,從而促進(jìn)內(nèi)皮細(xì)胞的增殖、遷移、存活和血管通透性的增加。VEGFA在生理性血管生成中的核心作用,如在胚胎發(fā)育、組織修復(fù)和女性生殖系統(tǒng)等過程中至關(guān)重要。此外,VEGFA在病理性血管生成中也起著關(guān)鍵作用,特別是在腫瘤血管生成、某些炎癥性疾病和年齡相關(guān)性眼病中,因此是多種疾病治療的重要靶點(diǎn)。

熱銷產(chǎn)品

Recombinant Human Vascular endothelial growth factor A (VEGFA) (CSB-YP025833HU)

驗(yàn)證數(shù)據(jù)

CSB-YP025833HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Vegfa Antibody (CSB-PA08249A0Rb)

驗(yàn)證數(shù)據(jù)

CSB-PA08249A0Rb

Western Blot
Positive WB detected in: Rat liver tissue
All lanes: Vegfa antibody at 4.8µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 26, 23, 21, 18 kDa
Observed band size: 26 kDa

CSB-PA08249A0Rb

Immunohistochemistry of paraffin-embedded mouse lung tissue using CSB-PA08249A0Rb at dilution of 1:100

Human Vascular Endothelial cell Growth Factor(VEGF) ELISA KIT (CSB-E11718h)

驗(yàn)證數(shù)據(jù)

CSB-E11718h 標(biāo)準(zhǔn)曲線

貨號(hào):CSB-E11718h

規(guī)格:96T/48T

靈敏度:25.297 pg/mL

檢測(cè)范圍:31.25 pg/mL-2000 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

VEGFA Antibodies

VEGFA for Pig

VEGFA for Homo sapiens (Human)

VEGFA for Rattus norvegicus (Rat)

VEGFA Proteins

VEGFA Proteins for Gallus gallus (Chicken)

VEGFA Proteins for Rattus norvegicus (Rat)

VEGFA Proteins for Homo sapiens (Human)

VEGFA Proteins for Bos taurus (Bovine)

VEGFA Proteins for Cavia porcellus (Guinea pig)

VEGFA Proteins for Sus scrofa (Pig)

VEGFA Proteins for Ovis aries (Sheep)

VEGFA Proteins for Coturnix coturnix japonica (Japanese quail) (Coturnix japonica)

VEGFA Proteins for Mesocricetus auratus (Golden hamster)

VEGFA Proteins for Equus caballus (Horse)

VEGFA Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

VEGFA ELISA Kit

VEGFA ELISA Kit for Bos taurus (Bovine)

VEGFA ELISA Kit for Canis lupus familiaris (Dog) (Canis familiaris)

VEGFA ELISA Kit for Homo sapiens (Human)

VEGFA ELISA Kit for Mus musculus (Mouse)

VEGFA ELISA Kit for Sus scrofa (Pig)

VEGFA ELISA Kit for Rattus norvegicus (Rat)