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IL4

IL4,即白細(xì)胞介素4,別名Interleukin4。它主要由活化的T淋巴細(xì)胞、肥大細(xì)胞、嗜堿性粒細(xì)胞產(chǎn)生。IL-4的作用機(jī)制涉及與特異性受體IL-4Rα結(jié)合,通過JAK-STAT信號通路發(fā)揮作用,促進(jìn)Th2細(xì)胞的增殖和分化,抑制Th1細(xì)胞的活性,影響B(tài)細(xì)胞的增殖和抗體類別轉(zhuǎn)換。IL-4是介導(dǎo)2型免疫反應(yīng)的關(guān)鍵細(xì)胞因子,對體液免疫和適應(yīng)性免疫的調(diào)節(jié)起著至關(guān)重要的作用,參與過敏性疾病、自身免疫性疾病、感染性疾病和腫瘤的免疫反應(yīng)。

熱銷產(chǎn)品

Recombinant Human Interleukin-4 (IL4) (Active) (CSB-MP011659HUd7)

驗證數(shù)據(jù)

CSB-MP011659HUd7

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CSB-MP011659HUd7

Activity
The ED50 as determined by the dose-dependent stimulation of the proliferation of TF-1 cells is 1.864-4.949 ng/mL.

IL4 Recombinant Monoclonal Antibody (CSB-RA240377A0HU)

驗證數(shù)據(jù)

CSB-RA240377A0HU

IHC image of CSB-RA240377A0HU diluted at 1:100 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

IL4 Antibodies

IL4 for Homo sapiens (Human)

IL4 for Dog

IL4 Proteins

IL4 Proteins for Capra hircus (Goat)

IL4 Proteins for Ovis aries (Sheep)

IL4 Proteins for Equus caballus (Horse)

IL4 Proteins for Bos taurus (Bovine)

IL4 Proteins for Macaca mulatta (Rhesus macaque)

IL4 Proteins for Felis catus (Cat) (Felis silvestris catus)

IL4 Proteins for Mus musculus (Mouse)

IL4 Proteins for Homo sapiens (Human)

IL4 Proteins for Canis lupus familiaris (Dog) (Canis familiaris)

IL4 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

IL4 Proteins for Rattus norvegicus (Rat)

IL4 Proteins for Meriones unguiculatus (Mongolian jird) (Mongolian gerbil)

IL4 Proteins for Cervus elaphus (Red deer)

IL4 Proteins for Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys)

IL4 Proteins for Bubalus carabanensis (Swamp type water buffalo) (Bubalus bubalis carabanensis)

IL4 Proteins for Ailuropoda melanoleuca (Giant panda)

IL4 Proteins for Boselaphus tragocamelus (Nilgai)

IL4 Proteins for Mesocricetus auratus (Golden hamster)

IL4 Proteins for Papio anubis (Olive baboon)

IL4 Proteins for Bubalus bubalis (Domestic water buffalo)

IL4 Proteins for Lama glama (Llama)

IL4 Proteins for Pan troglodytes (Chimpanzee)

IL4 Proteins for Oryctolagus cuniculus (Rabbit)

IL4 Proteins for Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus)

IL4 ELISA Kit

IL4 ELISA Kit for Bos taurus (Bovine)

IL4 ELISA Kit for Canis lupus familiaris (Dog) (Canis familiaris)

IL4 ELISA Kit for Capra hircus (Goat)

IL4 ELISA Kit for Homo sapiens (Human)

IL4 ELISA Kit for Mus musculus (Mouse)

IL4 ELISA Kit for Sus scrofa (Pig)

IL4 ELISA Kit for Oryctolagus cuniculus (Rabbit)

IL4 ELISA Kit for Rattus norvegicus (Rat)

IL4 ELISA Kit for Ovis aries (Sheep)

IL4 ELISA Kit for Mesocricetus auratus (Golden hamster)