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SLC27A1

Long-chain fatty acid transport protein 1 is a protein in humans that is encoded by SLC27A1 gene. Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. The LFCA import appears to be hormone-regulated in a tissue-specific manner. In adipocytes, but not myocytes, insulin induces a rapid translocation of FATP1 from intracellular compartments to the plasma membrane, paralleled by increased LFCA uptake. May act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane-associated multimeric protein complex to trap and draw fatty acids towards accumulation. Plays a pivotal role in regulating available LFCA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids (By similarity).

SLC27A1 Antibodies

SLC27A1 for Homo sapiens (Human)

SLC27A1 Proteins

SLC27A1 Proteins for Rattus norvegicus (Rat)

SLC27A1 Proteins for Bos taurus (Bovine)

SLC27A1 Proteins for Mus musculus (Mouse)

SLC27A1 Proteins for Homo sapiens (Human)