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SELP

SELP，全稱為selectin P (granule membrane protein 140kDa, antigen CD62)，是一種存在于血小板α顆粒和內(nèi)皮細胞Weibel-Palade小體中的跨膜糖蛋白。它也被稱為P-選擇素、GMP140、CD62P等。SELP蛋白在炎癥反應(yīng)中發(fā)揮著重要作用，介導(dǎo)中性粒細胞和單核細胞與內(nèi)皮細胞的初始粘附相互作用；在止血過程中，活化的血小板與中性粒細胞和單核細胞相互作用。SELP蛋白的表達和功能與多種疾病的發(fā)生發(fā)展密切相關(guān)，包括腎臟疾病、甲狀腺疾病、腫瘤等。近年來，研究發(fā)現(xiàn)SELP蛋白參與了多種腎臟疾病的病理生理過程，如腎缺血再灌注損傷、糖尿病腎病、慢性腎臟病及腎癌等。SELP蛋白的抗氧化活性可能在腎臟疾病的防治中發(fā)揮重要作用。此外，SELP蛋白的表達和功能也與甲狀腺疾病、腫瘤等密切相關(guān)。在藥物研發(fā)方面，針對SELP蛋白的抗體和重組蛋白等已被廣泛應(yīng)用于基礎(chǔ)研究和臨床診斷中，并成為潛在的治療靶點。

熱銷產(chǎn)品

Recombinant Human P-selectin (SELP), partial (CSB-MP020978HU)

驗證數(shù)據(jù)

CSB-MP020978HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

SELP Antibody (CSB-PA020978LA01HU)

驗證數(shù)據(jù)

CSB-PA020978LA01HU

Immunofluorescence staining of HepG2 cells with CSB-PA020978LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

Human P-Selectin ELISA kit (CSB-E04708h)

驗證數(shù)據(jù)

CSB-E04708h 標(biāo)準(zhǔn)曲線

貨號：CSB-E04708h

規(guī)格：96T/48T

靈敏度：0.225 ng/mL

檢測范圍：0.9 ng/mL-60 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

SELP Antibodies

SELP for Homo sapiens (Human)

產(chǎn)品貨號 產(chǎn)品名稱 種屬反應(yīng)性 應(yīng)用類型
CSB-PA006202 SELP Antibody Human,Mouse,Rat WB, ELISA
CSB-PA020978LA01HU SELP Antibody Human ELISA, IF
CSB-PA020978LB01HU SELP Antibody, HRP conjugated Human ELISA
CSB-PA020978LC01HU SELP Antibody, FITC conjugated Human
CSB-PA020978LD01HU SELP Antibody, Biotin conjugated Human ELISA

SELP Proteins

SELP Proteins for Ovis aries (Sheep)

產(chǎn)品貨號 產(chǎn)品名稱 來源
CSB-YP020978SH1
CSB-EP020978SH1
CSB-BP020978SH1
CSB-MP020978SH1
CSB-EP020978SH1-B
 Recombinant Sheep P-selectin (SELP), partial Yeast
E.coli
Baculovirus
Mammalian cell
In Vivo Biotinylation in E.coli
CSB-CF020978SH Recombinant Sheep P-selectin (SELP) in vitro E.coli expression system

SELP Proteins for Rattus norvegicus (Rat)

產(chǎn)品貨號 產(chǎn)品名稱 來源
CSB-YP020978RA1
CSB-EP020978RA1
CSB-BP020978RA1
CSB-MP020978RA1
CSB-EP020978RA1-B
 Recombinant Rat P-selectin (Selp), partial Yeast
E.coli
Baculovirus
Mammalian cell
In Vivo Biotinylation in E.coli
CSB-CF020978RA Recombinant Rat P-selectin (Selp) in vitro E.coli expression system

SELP Proteins for Mus musculus (Mouse)

產(chǎn)品貨號 產(chǎn)品名稱 來源
CSB-YP020978MO1
CSB-EP020978MO1
CSB-BP020978MO1
CSB-MP020978MO1
CSB-EP020978MO1-B
 Recombinant Mouse P-selectin (Selp), partial Yeast
E.coli
Baculovirus
Mammalian cell
In Vivo Biotinylation in E.coli
CSB-CF020978MO Recombinant Mouse P-selectin (Selp) in vitro E.coli expression system

SELP Proteins for Bos taurus (Bovine)

產(chǎn)品貨號 產(chǎn)品名稱 來源
CSB-YP020978BO1
CSB-EP020978BO1
CSB-BP020978BO1
CSB-MP020978BO1
CSB-EP020978BO1-B
 Recombinant Bovine P-selectin (SELP), partial Yeast
E.coli
Baculovirus
Mammalian cell
In Vivo Biotinylation in E.coli
CSB-CF020978BO Recombinant Bovine P-selectin (SELP) in vitro E.coli expression system

SELP Proteins for Homo sapiens (Human)

產(chǎn)品貨號 產(chǎn)品名稱 來源
CSB-MP020978HU Recombinant Human P-selectin (SELP), partial Mammalian cell

SELP ELISA Kit

SELP ELISA Kit for Homo sapiens (Human)

產(chǎn)品貨號 產(chǎn)品名稱 樣本類型 靈敏度
CSB-E04708h Human P-Selectin ELISA kit serum, plasma, tissue homogenates 0.225 ng/mL

SELP ELISA Kit for Mus musculus (Mouse)

產(chǎn)品貨號 產(chǎn)品名稱 樣本類型 靈敏度
CSB-E04709m Mouse P-Selectin ELISA kit serum, plasma, tissue homogenates 7.8 pg/mL

SELP ELISA Kit for Rattus norvegicus (Rat)

產(chǎn)品貨號 產(chǎn)品名稱 樣本類型 靈敏度
CSB-E07399r Rat P-Selectin ELISA kit serum, plasma, tissue homogenates 2.34 ng/mL