PROM1
PROM1，全名為Prominin-1，也被稱(chēng)為CD133，是一種在多種細(xì)胞類(lèi)型中廣泛表達(dá)的跨膜糖蛋白。它在造血干細(xì)胞、神經(jīng)干細(xì)胞以及多種組織中的上皮細(xì)胞中都有表達(dá)。PROM1在癌癥中扮演著重要角色，被鑒定為癌干細(xì)胞標(biāo)志物，與腫瘤的起始、發(fā)展和化療抵抗等相關(guān)聯(lián)。目前，針對(duì)PROM1的藥物研發(fā)正在積極推進(jìn)，已有多種針對(duì)PROM1的抗體藥物和免疫療法在研，主要用于癌癥治療，如膠質(zhì)母細(xì)胞瘤、卵巢上皮癌等。
熱銷(xiāo)產(chǎn)品
Recombinant Human Prominin-1 (PROM1)-VLPs (Active) (CSB-MP018751HU(A4))
驗(yàn)證數(shù)據(jù)
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CSB-MP018751HU(A4) is detected by Mouse anti-6*His monoclonal antibody.
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Activity
Measured by its binding ability in a functional ELISA. Immobilized PROM1 at 5 μg/mL can bind Anti-PROM1 recombinant antibody (CSB-RA018751MA1HU), the EC50 is 0.4322-0.7189 ng/mL.
PROM1 Recombinant Monoclonal Antibody (CSB-RA018751MA1HU)
驗(yàn)證數(shù)據(jù)
The Binding Activity of PROM1 with Anti-PROM1 recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized PROM1 (CSB-MP018751HU(A4)) at 5 μg/mL can bind Anti-PROM1 recombinant antibody, the EC50 is 0.4322-0.7189 ng/mL.
PROM1 Antibodies
PROM1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 種屬反應(yīng)性 | 應(yīng)用類(lèi)型 |
|---|---|---|---|
| CSB-PA018751GA01HU | PROM1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA005110 | PROM1 Antibody | Human,Mouse | WB, ELISA |
| CSB-PA212285 | PROM1 Antibody | Human,Mouse | ELISA,IHC |
| CSB-PA242765 | PROM1 Antibody | Human,Mouse | ELISA,IHC |
| CSB-PA018751LA01HU | PROM1 Antibody | Human | ELISA, WB, IHC |
| CSB-PA018751LB01HU | PROM1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA018751LC01HU | PROM1 Antibody, FITC conjugated | Human | |
| CSB-PA018751LD01HU | PROM1 Antibody, Biotin conjugated | Human | ELISA |
| CSB-RA018751MA1HU | PROM1 Recombinant Monoclonal Antibody | Human | ELISA |
PROM1 Proteins
PROM1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP018751HU | Recombinant Human Prominin-1 (PROM1), partial | Yeast |
| CSB-EP018751HU CSB-BP018751HU CSB-MP018751HU CSB-EP018751HU-B |
Recombinant Human Prominin-1 (PROM1), partial | E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-MP018751HU(A4) | Recombinant Human Prominin-1 (PROM1)-VLPs (Active) | Mammalian cell |
PROM1 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP018751MO CSB-BP018751MO CSB-MP018751MO CSB-EP018751MO-B |
Recombinant Mouse Prominin-1 (Prom1), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP018751MO | Recombinant Mouse Prominin-1 (Prom1),Partial | E.coli |
