PIK3C3
PIK3C3，即磷脂酰肌醇3-激酶催化亞基3型，別名VPS34、Vps34、hVps34。PIK3C3是磷脂酰肌醇3-激酶（PI3K）家族的成員，能夠磷酸化磷脂酰肌醇（PtdIns）生成磷脂酰肌醇3-磷酸（PI3P），這是自噬過程中的一個中心磷脂質(zhì)。PIK3C3在早期內(nèi)體到晚期內(nèi)體的轉(zhuǎn)運和細胞質(zhì)分裂的調(diào)節(jié)中發(fā)揮作用，位于自溶酶體、晚期內(nèi)體和中體。PIK3C3對于自噬的形成至關(guān)重要，自噬是細胞在環(huán)境變化時維持生存的機制，也幫助腫瘤細胞抵抗代謝應(yīng)激和癌癥治療。PIK3C3通過不依賴自噬的機制誘導(dǎo)腫瘤細胞的轉(zhuǎn)化和增強腫瘤細胞的增殖、生長和侵襲。PIK3C3在多種人類腫瘤中的表達模式和在腫瘤發(fā)生中的潛在機制，以及在癌癥生物學(xué)、患者預(yù)后預(yù)測和癌癥治療中的意義被廣泛研究。
熱銷產(chǎn)品
PIK3C3 Antibody (CSB-PA854108LA01HU)
驗證數(shù)據(jù)
Western Blot
Positive WB detected in: Hela whole cell lysate
All lanes: PIK3C3 antibody at 3.4μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 102 kDa
Observed band size: 102 kDa
Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA854108LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA854108LA01HU at dilution of 1:100
PIK3C3 Antibodies
PIK3C3 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA017997GA01HU | PIK3C3 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA909570 | PIK3C3 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA381950 | PIK3C3 Antibody | Human,Mouse,Rat,Cow | WB,ELISA |
| CSB-PA854108LA01HU | PIK3C3 Antibody | Human | ELISA, WB, IHC |
| CSB-PA854108LB01HU | PIK3C3 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA854108LC01HU | PIK3C3 Antibody, FITC conjugated | Human | |
| CSB-PA854108LD01HU | PIK3C3 Antibody, Biotin conjugated | Human | ELISA |
PIK3C3 Proteins
PIK3C3 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP017997RA CSB-EP017997RA CSB-BP017997RA CSB-MP017997RA CSB-EP017997RA-B |
Recombinant Rat Phosphatidylinositol 3-kinase catalytic subunit type 3 (Pik3c3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PIK3C3 Proteins for Sus scrofa (Pig)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP707708PI CSB-EP707708PI CSB-BP707708PI CSB-MP707708PI CSB-EP707708PI-B |
Recombinant Pig Phosphatidylinositol 3-kinase catalytic subunit type 3 (PIK3C3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PIK3C3 Proteins for Xenopus laevis (African clawed frog)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP731839XBE CSB-EP731839XBE CSB-BP731839XBE CSB-MP731839XBE CSB-EP731839XBE-B |
Recombinant Xenopus laevis Phosphatidylinositol 3-kinase catalytic subunit type 3 (pik3c3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PIK3C3 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP754257MO CSB-EP754257MO CSB-BP754257MO CSB-MP754257MO CSB-EP754257MO-B |
Recombinant Mouse Phosphatidylinositol 3-kinase catalytic subunit type 3 (Pik3c3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PIK3C3 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP854108HU CSB-EP854108HU CSB-BP854108HU CSB-MP854108HU CSB-EP854108HU-B |
Recombinant Human Phosphatidylinositol 3-kinase catalytic subunit type 3 (PIK3C3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
