亚洲一区二区三区中文字幂,在线观看免费人成视频色9,最近最新高清中文字幕,阳茎伸入阳道全过程视频,中出老熟女中文字幕

Your Good Partner in Biology Research

MARK2

MARK2 is a protein in humans that is encoded by MARK2 gene. Serine/threonine-protein kinase. Involved in cell polarity and microtubule dynamics regulation. Phosphorylates CRTC2/TORC2, DCX, HDAC7, KIF13B, MAP2, MAP4 and RAB11FIP2. Phosphorylates the microtubule-associated protein MAPT/TAU. Plays a key role in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Regulates epithelial cell polarity by phosphorylating RAB11FIP2. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Regulates axogenesis by phosphorylating KIF13B, promoting interaction between KIF13B and 14-3-3 and inhibiting microtubule-dependent accumulation of KIF13B. Also required for neurite outgrowth and establishment of neuronal polarity. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3).

MARK2 Antibodies

MARK2 for Homo sapiens (Human)

MARK2 Proteins

MARK2 Proteins for Mus musculus (Mouse)

MARK2 Proteins for Rattus norvegicus (Rat)

MARK2 Proteins for Homo sapiens (Human)