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FZD10

Frizzled-10 is a protein in humans that is encoded by FZD10 gene. Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.

FZD10 Antibodies

FZD10 for Homo sapiens (Human)

FZD10 Proteins

FZD10 Proteins for Mus musculus (Mouse)

FZD10 Proteins for Gallus gallus (Chicken)

FZD10 Proteins for Homo sapiens (Human)