ABCD1
ABCD1是一種定位于過氧化物酶體膜上的ATP結(jié)合盒式轉(zhuǎn)運蛋白，具有特定的結(jié)構(gòu)和功能。它利用ATP水解的能量，將超長鏈脂肪酸轉(zhuǎn)運至過氧化物酶體進行β-氧化，維持細胞內(nèi)脂質(zhì)平衡。ABCD1的結(jié)構(gòu)特點包括兩個核苷酸結(jié)合結(jié)構(gòu)域和兩個跨膜結(jié)構(gòu)域，這些結(jié)構(gòu)域在底物結(jié)合時發(fā)生構(gòu)象變化，實現(xiàn)底物的轉(zhuǎn)運。然而，當(dāng)ABCD1功能障礙時，會導(dǎo)致超長鏈脂肪酸在細胞質(zhì)基質(zhì)中異常積累，從而引發(fā)X-連鎖腎上腺腦白質(zhì)營養(yǎng)不良等神經(jīng)退行性疾病。
熱銷產(chǎn)品
Recombinant Human ATP-binding cassette sub-family D member 1 (ABCD1)-VLPs
CSB-MP001068HU
ABCD1 Antibodies
ABCD1 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA001068GA01HU | ABCD1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA214656 | ABCD1 Antibody | Human | ELISA,WB |
| CSB-PA008163 | ABCD1 Antibody | Human | WB, ELISA |
| CSB-PA001068LA01HU | ABCD1 Antibody | Human | ELISA, IHC |
ABCD1 Proteins
ABCD1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP001068HU1 CSB-EP001068HU1 CSB-BP001068HU1 CSB-MP001068HU1 CSB-EP001068HU1-B |
Recombinant Human ATP-binding cassette sub-family D member 1 (ABCD1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF001068HU | Recombinant Human ATP-binding cassette sub-family D member 1 (ABCD1) (Active) | in vitro E.coli expression system |
| CSB-MP001068HU | Recombinant Human ATP-binding cassette sub-family D member 1 (ABCD1)-VLPs | Mammalian cell |
