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  4. LY6G6D Recombinant Monoclonal Antibody

LY6G6D Recombinant Monoclonal Antibody

  • 中文名稱：
    LY6G6D重組抗體
  • 貨號(hào)：
    CSB-RA013246MA1HU
  • 規(guī)格：
    ￥1320
  • 圖片：
    • The Binding Activity of LY6G6D with anti-LY6G6D antibody
      Activity: Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis LY6G6D(CSB-YP4607MOV) at 2 μg/mL can bind Anti-LY6G6D recombinant antibody, the EC50 is 3.963-7.154 ng/mL.
    • The Binding Activity of LY6G6D with anti-LY6G6D antibody
      Activity: Measured by its binding ability in a functional ELISA. Immobilized Human LY6G6D(CSB-YP013246HU) at 2 μg/mL can bind Anti-LY6G6D recombinant antibody, the EC50 is 2.816-3.741 ng/mL.
    • Untransfected HEK293T cells surface (green line) and transfected Human LY6G6D HEK293T stable cells surface(red line) were stained with anti-LY6G6D antibody (CSB-RA013246MA1HU) (2μg/1*106cells), washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    CSB-RA013246MA1HU 重組單克隆抗體是針對(duì)人源LY6G6D蛋白開發(fā)的高特異性科研工具。LY6G6D（淋巴細(xì)胞抗原6復(fù)合物基因座G6D）是LY6/uPAR蛋白家族成員，在免疫細(xì)胞表面選擇性表達(dá)，其與腫瘤免疫逃逸及T細(xì)胞功能調(diào)控相關(guān)，是腫瘤微環(huán)境研究的重要靶點(diǎn)。該抗體經(jīng)ELISA驗(yàn)證具有高親和力，可精準(zhǔn)識(shí)別天然構(gòu)象的LY6G6D抗原；流式細(xì)胞術(shù)（FC）數(shù)據(jù)顯示其能有效區(qū)分LY6G6D陽性和陰性細(xì)胞群，適用于活細(xì)胞表面標(biāo)記檢測(cè)。推薦用于腫瘤免疫機(jī)制研究、免疫細(xì)胞亞群分型及靶向藥物開發(fā)中的靶點(diǎn)驗(yàn)證，尤其適用于流式多色分析中與CD3、CD8等標(biāo)記物的共定位研究，為探索LY6G6D在腫瘤免疫治療中的功能提供可靠工具。本產(chǎn)品采用重組表達(dá)技術(shù)制備，具備優(yōu)異的批次穩(wěn)定性和低交叉反應(yīng)性，滿足高通量篩選及功能性實(shí)驗(yàn)對(duì)抗體一致性的嚴(yán)苛要求。
  • Uniprot No.：
  • 基因名：
  • 別名：
    Lymphocyte antigen 6 complex locus protein G6d; Protein Ly6-D; Megakaryocyte-enhanced gene transcript 1 protein; LY6G6D; C6orf23; G6D; MEGT1; NG25
  • 反應(yīng)種屬：
    Human, Macaca fascicularis
  • 免疫原：
    Recombinant Human LY6G6D protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    hIgG1
  • 純化方式：
    Affinity-chromatography
  • 克隆號(hào)：
    8I8
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, FC
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 基因功能參考文獻(xiàn)：
    1. Frequencies of the DRB1, DQA1, DQB1 and TNFA alleles in immigrant population of West Siberia PMID: 19807019
  • 亞細(xì)胞定位：
    Cell membrane; Lipid-anchor, GPI-anchor. Cell projection, filopodium.
  • 組織特異性：
    Expressed in the adult lung, and in fetal liver, lung, kidney, brain and spleen.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 13935

    OMIM: 606038

    KEGG: hsa:58530

    STRING: 9606.ENSP00000364985

    UniGene: Hs.591792